Starting Sustiva (efavirenz)? You’re not alone. This antiretroviral is effective against HIV but often causes side effects people want to know about up front. Below I’ll walk you through common symptoms, what can be serious, how drugs can interact, and simple ways to manage problems day-to-day.
Most people notice central nervous system (CNS) symptoms in the first days or weeks: dizziness, vivid dreams or nightmares, trouble sleeping, and trouble concentrating. These usually improve after a few weeks as your body adjusts. Nausea and headache can happen too, often mild and manageable.
Skin rash is another frequent issue. Many rashes are mild and fade on their own, but any rapidly spreading rash, blisters, or fever with rash needs urgent care. Liver effects can occur — watch for yellowing of the skin or eyes, dark urine, or severe abdominal pain.
Changes in cholesterol or triglycerides have been reported, so routine blood tests may show shifts that your doctor will monitor.
Sustiva affects liver enzymes that process many drugs. That means some medicines may work less well or cause more side effects when taken with efavirenz. Examples to watch for: certain hormonal birth control methods (pill or implant), some benzodiazepines, and drugs used for other infections or chronic conditions. Always tell every clinician and pharmacist that you take efavirenz.
If you’re pregnant or planning pregnancy, bring this up with your provider. Treatment choices can change based on pregnancy plans and timing.
Seek medical help right away for severe rash, signs of liver trouble, new severe mood changes, thoughts of self-harm, or if you faint or have seizures.
Practical tips that help
Take Sustiva at bedtime with or without food — many people sleep through dizziness and vivid dreams that way. Avoid driving or heavy machinery until you know how Sustiva affects you. If nausea is a problem, try taking it after a light snack and talk to your provider about options.
Ask your clinic for baseline blood tests (liver enzymes, lipids) and follow-up checks. If you use hormonal birth control, discuss extra precautions like condoms or a partner’s vasectomy to avoid pregnancy surprises.
If side effects don’t improve or are severe, there are alternative HIV medicines with fewer CNS effects. Your clinician can suggest a safer option based on your overall health and other meds you take.
Quick recap: expect some CNS effects early on, watch skin and liver signs, be mindful of drug interactions, and contact your healthcare team if anything serious shows up. Keeping open communication with your provider makes managing side effects easier and keeps your treatment on track.
Sustiva (efavirenz) is a common HIV medication. Learn about uses, side effects, dosage information, tips for taking, and important facts in this detailed article.
Continue reading...
