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Narcolepsy with Cataplexy: How It’s Diagnosed and Why Sodium Oxybate Is the Gold Standard Treatment

Narcolepsy with Cataplexy: How It’s Diagnosed and Why Sodium Oxybate Is the Gold Standard Treatment

Narcolepsy with cataplexy is a rare neurological disorder causing uncontrollable sleepiness and sudden muscle weakness triggered by emotions. Diagnosis requires specialized sleep tests and CSF hypocretin testing. Sodium oxybate (Xyrem/Xywav) is the only treatment proven to reduce both cataplexy and daytime sleepiness.

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Nov 28, 2025 dave smith 0

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